WASHINGTON—The Senate is expected at noon Tuesday to sign off on a bipartisan agreement to raise the federal debt ceiling and cut as much as $2.4 trillion from budget deficits, after the House passed the measure 269-161 last night.

The deal is the product of one of the most ferocious fights ever over government spending and political brinksmanship that caused economic uncertainty and continues to threaten the nation’s prized AAA credit rating. Its passage through the Senate makes it likely that Congress won’t break Tuesday’s deadline set by the Treasury Department after which the nation could run out of money to pay all of its bills.

Passage in the House came despite the opposition of both conservative Republicans and liberal Democrats, both of whom balked at the deal reached over the weekend between President Barack Obama and congressional leaders.

However, the agreement was expected to obtain the 60 votes needed for it to pass the Senate, paving the way for Mr. Obama to sign it into law Tuesday afternoon.

“Finally Washington is taking some responsibility for spending money that we don’t have,” said Sen. Lamar Alexander (R., Tenn.) on the Senate floor, who said he would support it. “Make no mistake, this is a change in behavior, from spend, spend, spend to cut, cut, cut.”

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